The best Side of cees dekker

The best Side of cees dekker

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Reconstitution of ultrawide DNA origami pores in liposomes for transmembrane transport of macromolecules

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I can hardly imagine how I, to be a geneticist, would manage to master elementary physics, let alone compete at the best. How did you go over it?

2010, created a whole new way (‘wedging transfer’) to govern nanostructures; to start with report of DNA translocation through graphene nanopores; and realized hybrid nanopores by directed insertion of α-hemolysin into sound-condition nanopores

SMC complexes can pass Actual physical roadblocks larger than their ring measurement, indicating a nontopological mechanism for DNA loop extrusion

All parameters were being the same for each panel Within this video clip, apart from the First placement with the 6hb rod (revealed in blue) over the nanopore. Simulations that terminated early because of translocation in the rod throughout the pore are marked by a grey qualifications.

2011, initially in vitro measurements of transportation across just one biomimetic nuclear pore complicated; advancement of multiplexed magnetic tweezers for kilo-molecule experiments; and settled the mechanism of homology recognition in DNA homologous recombination

2003, shown the main biosensors built away from a carbon nanotube; solved the construction and mechanism of DNA maintenance proteins; and discovery of a completely new procedure for fabricating stable-condition nanopores for DNA translocation

one). The present–voltage curves confirmed considerable modulations with gate voltage, even at space temperature, which was in keeping with band bending within a ~0.six eV bandgap semiconducting nanotube. These info also confirmed that the conductance may be modulated by six orders of magnitude by shifting the gate voltage. The results of this do the job — a space-temperature transistor comprised of just one carbon nanotube molecule — ended up published in Character in May perhaps 1998.

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2008, initially observation of protein-coated DNA translocation by nanopores; solved the origin on the electrophoretic pressure on DNA in https://www.ceesdekker.net nanopores; uncovered a major velocity boost of microtubules in electrical fields; found an anomalous electro-hydrodynamic orientation of microtubules; and resolved the origin of sounds in carbon nanotubes in liquid

2004, discovery of recent physics in translocation of DNA by way of nanopores; initial experimental study of ions conduction in nanofluidic channels; initially electrochemistry with personal one-wall carbon nanotubes; STM detection and Charge of phonons in carbon nanotubes; initial electrical docking of microtubules on kinesin-coated nanostructures; to start with biophysics characterization on the mechanical Qualities of double-stranded RNA; and to start with solitary-molecule research of DNA translocation by a restriction-modification enzyme.